← Research · PLoS Genetics (University of Washington, Fred Hutch)

INX-18 and INX-19 play distinct roles in electrical synapses that modulate aversive behavior

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Genetics · Behavioral Neuroscience

Electrical synapses are critical for fast neural communication. This paper elucidates the distinct functional roles of innexin proteins INX-18 and INX-19 in forming gap junctions that modulate aversive behavioral responses in Caenorhabditis elegans, contributing to our understanding of the genetic basis of behavior.

Notes

Wet-lab genetics on how neurons pass signals to each other electrically, rather than chemically — which gap-junction proteins wire which connections, and what changes in an animal’s behaviour when you take one away.

It sits on this site as evidence rather than as a headline. The thesis running through everything here is signal: measuring one, reading one, deciding what it means. This is where that started literally, in a nervous system you can count the cells of.