AI systems architect · research to production

Bishal Upadhyaya.

Vibeset

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Research

Systems Architecture & Intelligence Analysis

2023

A Generalization of Continuous Relaxation in Structured Pruning

Nvidia, Thermo Fisher Scientific (arXiv)

with Brad Larson, Luke McDermott, Siddha Ganju

Deep LearningStructured PruningComputer VisionEfficient AI
2023

A Generalization of Continuous Relaxation in Structured Pruning

Structured pruning asserts that while large networks enable us to find solutions to complex computer vision problems, a smaller, computationally efficient sub-network can be extracted. We propose a generalization of continuous relaxation in structured pruning to effectively identify these optimal sub-networks, ensuring performance on resource-constrained hardware.

2021

Circumventing neural damage in a C. elegans chemosensory circuit using genetically engineered synapses

Cell Systems (University of Washington, Fred Hutch)

with Dr. Sreekanth Chalasani, Research Team

NeuroscienceC. elegansNeural EngineeringConnectomics
2021

Circumventing neural damage in a C. elegans chemosensory circuit using genetically engineered synapses

Investigating neural circuit plasticity, this study demonstrates how genetically engineered electrical synapses can reroute information flow to circumvent damaged neurons. By expressing connexin gap junctions, we successfully restored chemotaxis behavior in C. elegans after critical interneuron loss, highlighting the potential of artificial synapses in neural repair.

2020

A Comparison of FDG and Amyloid PET for the Deep Learning Prediction of Alzheimer’s Disease

University of California, San Francisco

with Research Group

Alzheimer'sDeep LearningMedical ImagingHealthcare Equity
2020

A Comparison of FDG and Amyloid PET for the Deep Learning Prediction of Alzheimer’s Disease

This research compares the efficacy of FDG PET (metabolic) and Amyloid PET (pathological) biomarkers in training Deep Learning models for Alzheimer's prediction. The study focuses on applying these models to data from underprivileged communities, evaluating accessibility versus predictive power for early diagnosis.

2019

INX-18 and INX-19 play distinct roles in electrical synapses that modulate aversive behavior

PLoS Genetics (University of Washington, Fred Hutch)

with Lab Colleagues

GeneticsBehavioral NeuroscienceGap JunctionsC. elegans
2019

INX-18 and INX-19 play distinct roles in electrical synapses that modulate aversive behavior

Electrical synapses are critical for fast neural communication. This paper elucidates the distinct functional roles of innexin proteins INX-18 and INX-19 in forming gap junctions that modulate aversive behavioral responses in Caenorhabditis elegans, contributing to our understanding of the genetic basis of behavior.

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